Massive Selection for Occult Blood Test Principle - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody
Massive Selection for Occult Blood Test Principle - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.
2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.
Product detail pictures:
Related Product Guide:
We are commitment to offer you the aggressive price tag ,exceptional products and solutions high-quality, as well as fast delivery for Massive Selection for Occult Blood Test Principle - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Jamaica, Johor, London, Our stock have valued 8 million dollar , you can find the competitive parts within short delivery time. Our company is not only your partner in business, but also our company is your assistant in the coming corporation.
By Miranda from Sevilla - 2018.06.21 17:11
The factory workers have rich industry knowledge and operational experience, we learned a lot in working with them,we are extremely grateful that we can encount a good company has excellent wokers.
By Sabina from South Korea - 2017.12.31 14:53
