Manufacturer for Antigen Test Kit - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody
Manufacturer for Antigen Test Kit - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has been used previously to quantify the number of neutrophils in tissue. MPO activity was found to be linearly related to the number of neutrophil cells. The MPO system plays an important role in the control of infections and the deletion of malignant cells. Nevertheless, alternations in the MPO system can lead to DNA damage and carcinogenesis. Polymorphisms in the MPO gene have been associated with an increased expression of MPO and a higher risk for the development of cancer. Myeloperoxidase (MPO) is one of the major target antigens of antineutrophil cytoplasmic autoantibodies (ANCA) found in patients with small-vessel vasculitis and Pauci-immune necrotizing glomerulonephritis. Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) is an autoantibody that is frequently found in patients with vasculitides.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 4D12-3 ~ 2C1-8 4C16-1 ~ 2C1-8 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| MPO | AB0007-1 | 2C1-8 |
| AB0007-2 | 4D12-3 | |
| AB0007-3 | 4C16-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Klebanoff, S. J . Myeloperoxidase: friend and foe[J]. J Leukoc Biol, 2005, 77(5):598-625.
2.Baldus, S. Myeloperoxidase Serum Levels Predict Risk in Patients With Acute Coronary Syndromes[J]. Circulation, 2003, 108(12):1440.
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continue on to further improve, to make sure product top quality in line with market and consumer standard requirements. Our firm has a excellent assurance program have already been established for Manufacturer for Antigen Test Kit - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Lisbon, UAE, Rio de Janeiro, Our tenet is "integrity first, quality best". We have confidence in providing you with excellent service and ideal products. We sincerely hope we can establish win-win business cooperation with you in the future!
By Nina from Argentina - 2017.09.29 11:19
We feel easy to cooperate with this company, the supplier is very responsible, thanks.There will be more in-depth cooperation.
By Pamela from Bandung - 2018.12.11 11:26
