Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody
Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
| Bioantibody | Clinically Diagnosed Case | Total | |
| Positive | Negative | ||
| Positive | 35 | 0 | 35 |
| Negative | 1 | 87 | 88 |
| Total | 36 | 87 | 123 |
| Specificity | 100% | ||
| Sensitivity | 97% | ||
Order Information
| Product Name | Cat. No | Clone ID |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.
2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.
Product detail pictures:
Related Product Guide:
We pursue the administration tenet of "Quality is superior, Services is supreme, Standing is first", and will sincerely create and share success with all customers for Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: South Korea, Las Vegas, Jordan, We follow superior mechanism to process these products that ensure optimum durability and reliability of the products. We follow latest effective washing and straightening processes that allow us to offer unmatched quality of products for our clients. We continually strive for perfection and all our efforts are directed towards attaining complete client satisfaction.
By Jane from Colombia - 2018.11.06 10:04
The company leader recept us warmly, through a meticulous and thorough discussion, we signed a purchase order. Hope to cooperate smoothly
By Caroline from Sri Lanka - 2018.06.18 17:25
