Leading Manufacturer for Faecal Blood Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody

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Leading Manufacturer for Faecal Blood Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:

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General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

Properties

Pair Recommendation	CLIA (Capture-Detection): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

Bioantibody	clinically diagnosed case		Total
Bioantibody	positive	Negative	Total
positive	46	3	49
Negative	4	97	101
Total	50	100	150
evaluation index	sensitivity	specificity	accuracy
evaluation index	92%	97%	95%

Order Information

Product Name	Cat. No	Clone ID
CHI3L1	AB0031-1	1G11-14
	AB0031-2	2E4-2
	AB0031-3	3A12-1
	AB0031-4	13F3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.

2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.

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We now have our own gross sales team, style and design workforce, technical crew, QC workforce and package group. We now have strict quality manage procedures for each system. Also, all of our workers are experienced in printing industry for Leading Manufacturer for Faecal Blood Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Portugal, Sheffield, Mali, We have established long-term, stable and good business relationships with many manufacturers and wholesalers around the world. Currently, we are looking forward to even greater cooperation with overseas customers based on mutual benefits. Please feel free to contact us for more details.

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We always believe that the details decides the company's product quality, in this respect, the company conform our requirements and the goods are meet our expectations.

By Nicole from Sao Paulo - 2017.10.27 12:12

This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.

By Carey from Doha - 2018.12.14 15:26

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