Factory For Lateral Flow Test Antigen - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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Factory For Lateral Flow Test Antigen - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation	CLIA (Capture-Detection): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4.
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name	Cat. No	Clone ID
GDF-15	AB0038-1	3A2-1
	AB0038-2	23F1-5
	AB0038-3	6C1-9
	AB0038-4	4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.

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We believe that long term partnership is a result of high quality, value added service, rich experience and personal contact for Factory For Lateral Flow Test Antigen - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Algeria, Maldives, United States, Look forward to the future, we will focus more on the brand building and promotion . And in the process of our brand global strategic layout we welcome more and more partners join us, work together with us based on mutual benefit. Let's develop market by fully utilizing our comprehensive advantages and strive for building.

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