Cheap price Pg Ii - Anti-human IL6, Mouse Monoclonal – Bioantibody

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General Information
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.

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Competitive Comparison

Correlation analysis-<120pg/mL

Correlation analysis -1.5-5000pg/mL

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Note: Bioantibody can customized quantities per your need.

Citations

1.Zhong Z , Darnell Z W , Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6[J]. Science, 1994.

2.J, Bauer, F, et al. Interleukin-6 in clinical medicine[J]. Annals of Hematology, 1991.