Bottom price Test Pack Antigen - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody
Bottom price Test Pack Antigen - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has been used previously to quantify the number of neutrophils in tissue. MPO activity was found to be linearly related to the number of neutrophil cells. The MPO system plays an important role in the control of infections and the deletion of malignant cells. Nevertheless, alternations in the MPO system can lead to DNA damage and carcinogenesis. Polymorphisms in the MPO gene have been associated with an increased expression of MPO and a higher risk for the development of cancer. Myeloperoxidase (MPO) is one of the major target antigens of antineutrophil cytoplasmic autoantibodies (ANCA) found in patients with small-vessel vasculitis and Pauci-immune necrotizing glomerulonephritis. Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) is an autoantibody that is frequently found in patients with vasculitides.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 4D12-3 ~ 2C1-8 4C16-1 ~ 2C1-8 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| MPO | AB0007-1 | 2C1-8 |
| AB0007-2 | 4D12-3 | |
| AB0007-3 | 4C16-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Klebanoff, S. J . Myeloperoxidase: friend and foe[J]. J Leukoc Biol, 2005, 77(5):598-625.
2.Baldus, S. Myeloperoxidase Serum Levels Predict Risk in Patients With Acute Coronary Syndromes[J]. Circulation, 2003, 108(12):1440.
Product detail pictures:
Related Product Guide:
Our focus on should be to consolidate and enhance the quality and repair of present products, in the meantime constantly establish new products to meet unique customers' requires for Bottom price Test Pack Antigen - Anti-human MPO Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Johor, Bangladesh, Leicester, By adhering to the principle of "human oriented, winning by quality", our company sincerely welcomes merchants from at home and abroad to visit us, talk business with us and jointly create a brilliant future.
By Roxanne from Morocco - 2017.10.13 10:47
The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
By Debby from Kuala Lumpur - 2018.10.01 14:14
