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8 Year Exporter Rapid Antigen Test For Dengue - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Properties
Pair Recommendation |
CLIA (Capture-Detection):
4H6-2 ~ 4C2-3
4H6-2 ~ 2H11-1 |
Purity |
>95% as determined by SDS-PAGE. |
Buffer Formulation |
20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Storage |
Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Bioantibody |
Clinically Diagnosed Case |
Total |
Positive |
Negative |
Positive |
35 |
0 |
35 |
Negative |
1 |
87 |
88 |
Total |
36 |
87 |
123 |
Specificity |
100% |
Sensitivity |
97% |
Order Information
Product Name |
Cat. No |
Clone ID |
IGFBP-1 |
AB0028-1 |
4H6-2 |
AB0028-2 |
4C2-3 |
AB0028-3 |
2H11-1 |
AB0028-4 |
3G12-11 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.
2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.
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