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100% Original Nt-Probnp - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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100% Original Nt-Probnp - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation CLIA (Capture-Detection):
23F1-5 ~ 6C1-9
23F1-5 ~ 3A2-1
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
GDF-15 AB0038-1 3A2-1
AB0038-2 23F1-5
AB0038-3 6C1-9
AB0038-4 4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.


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100% Original Nt-Probnp - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures

100% Original Nt-Probnp - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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We rely upon strategic thinking, constant modernisation in all segments, technological advances and of course upon our employees that directly participate in our success for 100% Original Nt-Probnp - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Malta, Greek, Panama, Abiding by our motto of "Hold well the quality and services, Customers Satisfaction", So we give our clients with high quality products and solutions and excellent service. Be sure to feel free to contact us for further information.
  • We have been cooperated with this company for many years, the company always ensure timely delivery ,good quality and correct number, we are good partners.
    5 Stars By Sara from El Salvador - 2017.08.18 18:38
    The customer service reprersentative explained very detailed, service attitude is very good, reply is very timely and comprehensive, a happy communication! We hope to have a opportunity to cooperate.
    5 Stars By Martha from Croatia - 2018.06.18 17:25
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